Hubungi sekarang juga - Kami mengerjakan tugas kuliah kedokteran , makalah, paper, proposal skripsi, tugas akhir, dijamin orisinil dan otentik. 0812 1944 9060

Hubungi sekarang juga - Kami mengerjakan tugas kuliah kedokteran , makalah, paper, proposal skripsi, tugas akhir, dijamin orisinil dan otentik.  0812 1944 9060

Jurnal yang sering digunakan untuk penelitian kedokteran:

•             Cancer

•             Nutrition & Cancer

•             Journal of Clinical Oncology

•             Journal of the National Cancer Institute

•             Cancer Research

•             Integrative Cancer Therapies

•             American Journal of Clinical Nutrition

•             Alternative Medicine Review

•             International Journal of Cancer

•             Clinical Pearls

•             Anticancer Research

•             Townsend Letter for Doctors & Their Patients

WEB RESOURCES

•             www.oncanp.org

•             www.aicr.org

•             www.lifeovercancer.com

•             www.cancerfacts.com

•             www.nci.nih.gov

•             www.cancernet.nci.nih.gov/clinpdq

•             www.cancer.org      American Cancer Society  1-800-ACS-2345

•             www.cdc.gov.org/cancer

•             www.bccancer.bc.ca

•             www.y-me.org

•             www.asco.org

•             www.Medscape.com  - oncology database

•             www.inspirehealth.ca

•             www.denvernaturopathic.com

•             www.camresearch.net

•             www.ncbi.nlm.nih.gov/PubMed/ 

•             www.oncologystat.com 

•             www.epec.net

•             www.lifeovercancer.com

Topic penelitian yang sedang menarik yang dapat anda gunakan untuk diteliti:

Antitumor and Radiosensitizing Effects of Withania somnifera (Ashwagandha) on a Transplantable Mouse Tumor, Sarcoma -180.  Devi & Solomon  Ind. J. Exp. Biol. July 1993; 31 (7): 607-611.

In vivo Growth Inhibitory Effect of Withania somnifera ( Ashwagandha) on a Transplantable Mouse Tumor Sarcoma-180, Devi, Sharada, Solomon, et al., Ind. J. Exp. Biol. 1992; 30: 169-172.

Withania somnifera dunal: Potential Plant Source of a Promising Drug for Chemotherapy and Radiosensitization, Devi, Ind. J. Exp. Biol. 1996; 34 (10): 927-932.

In vivo growth Inhibitory and Radiosensitizing Effects of Withaferin A on Mouse Erlich Ascites Carcinoma in vivo, Devi, Sharada & Solomon, Acat. Oncol. 1996; 35: 95-100.

Modulation of TCA Cycle Enzymes and Electron Transport Chain Systems (by Withania) In Experimental Lung Cancer, Senhilnathan, Padmavathi, Magesh & Sakthisekaran, Life Sci. 2006; 78 (9): 1010-1014.

Immunoprotection by Botanical Drugs in Cancer Chemotherapy, Diwanay, Chitre & Patwardhan,  J. Ethnopharmacol. 2004; 90 (1): 49-55

The Protective Effect of a Purified Extract of Withania somnifera Against Doxorubicin-induced Cardiac Toxicity in Rats, Hamza, Amin & Daoud,  Cell Biol. Toxicol. 2008; 24 (1): 63-73.

Enhancement of the Response of B16F1 |Melanoma to Fractionated Radiotherapy and Prolongation of Survival by Withaferin and/or Hyperthermia, Kalthur & Pathirissery, Integr. Cancer Ther. 2010; 9 (4): 370-377.

AVEMAR

Fermented Wheat Germ Extract (Avemar) in the Treatment of Cancer and Autoimmune Diseases, Boros, Nichelatti & Shoenfeld, Ann. N.Y. Acad. Sci. 2005; 1051: 529-542.

Antimetastatic Effect of Avemar in High-risk Melanoma Patients, Demidov, Manzjuk, Kharkevitch, et. al., 18th UICC International Cancer Congress, 2002; P868 - Oslo, Norway.

Adjuvant Fermented Wheat Germ Extract (Avemar) Nutraceutical Improves Survival of High-Risk Melanoma Patients: A Randomized, Pilot, Phase II Clinical Study with a 7-Year Follow-Up, Demidov, Manzuik, Kharkevitch, et al., Cancer Biother. Radiopharm. 2008; 23 (4): 477-482.

A Medical Nutriment Has Supportive Value in the Treament of Colorectal Cancer, Jakab, Schoenfeld, Balogh, et al., Br. J. Cancer 2003; 89 (3): 465-469.

Fermented Wheat Germ Extract Reduces Chemotherapy-Induced Febrile Neutropenia in Pediatric Cancer Patients, Garami, Schuler, Babosa, et al., J. Pediatr. Hematol. Oncol. 2004; 26 (10): 631–635.

Promising Cytotoxic Activity Profile of Fermented Wheat Germ Extract (Avemar®) in Human Cancer Cell Lines, Mueller, Jordan & Voigt, J. Exp. Clin. Cancer Res. 2011; 30: 42.

BOSWELLIA

Analysis of Frankincense from Various Boswellia Species with Inhibitory Activity on Human Drug Metabolising Cytochrome P450 Enzymes Using Liquid Chromatography Mass Spectrometry After Automated On-line Extraction, Frank & Unger, J. Chromatogr. A. 2006; 1112 (1-2): 255-262.

Boswellic Acids and Malignant Glioma: Induction of Apoptosis but No Modulation of Drug Sensitivity, Glaser, Winters, Groscurth, et. al., Br. J. Cancer 1998; 80 (5-6): 756-765.

Boswellic Acids Inhibit Glioma Growth: A New Treatment Option?, Winking, Sarikaya, et. al., J. Neurooncol  2000; 46: 97-103.

Boswellic Acids in the Palliative Therapy of Children with Progressive or Relapsed Brain Tumors, Janssen, Bode, Breu, et. al., Klin. Paediatr. 2000; 212: 189-195.

Response of Radio-Chemotherapy-associated Cerebral Edema to a Phytotherapeutic Agent H15, Streffer, Bitzer, Schabet, et al., Neurology 2001; 56: 1219-1221.

Boswellic Acid Acetate Induces Differentiation and Apoptosis in Leukemia Cell Lines, Jing, Nakato, et al., Leuk. Res. 1999; 23: 43-50.

Boswellic Acids: Novel, Specific, Non-redox Inhibitors of 5-lipoxygenase, Safayhi, Mack, Sabieraj, et al., J. Pharmacol. Exp. Ther. 1992; 261 (3): 1143-1146.

[Boswellia] A Lipoxygenase Inhibitor in Breast Cancer Brain Metastases, Flavin, J. Neurooncol. 2007; 82 (1): 91-93. Epub 2006 Sep 26.

BREAST CANCER

Survival Impact of Integrative Cancer Care in Advanced Metastatic Breast Cancer, Block, Gyllenhaal, Tripathy, et al., Breast J. 2009; 154: 357-366.

Apparent Partial Remission of Breast Cancer in “High-Risk” Patients Supplemented with Nutritional Antioxidants, Essential fatty acids and Coenzyme Q10,  Lockwood, Moesgaard, Hanioka, et. al., Mol. Aspects. Med. 1994; Suppl. 15: 231-240.

Progress on Therapy of Breast Cancer with Vitamin Q10 and the Regression of Metastases, Lockwood, Moesgaard, Yamamoto & Folkers, Biochem. Biophys. Res. Commun. 1995; 212 (1): 172-177.

The Israeli Breast Cancer Anomaly, Westin & Richter, Annals N.Y. Acad. Sci.  1989; 609: 269-279.

Alteration of the Effects of Cancer Therapy Agents on Breast Cancer Cells by the Herbal Medicine Black Cohosh, Rockwewll, Liu & Higgins, Breast Cancer Res. Treat. 2005; 90: 233-239.

Fibroblasts Isolated from Common Sites of Breast Cancer Metastasis Enhance Cancer Cell Growth Rates and Invasiveness in an Interleukin-6-Dependent Manner, Studebaker, Storci, Werbeck, et al., Cancer Res. 2008; 68 (21): 9087-9095.

Psychologic Intervention Improves Survival for Breast Cancer Patients: A Randomized Clinical Trial, Andersen, Yang, Farrar, et al., Cancer 2008; 113:3450-3458.

Perspectives on the Soy-Breast Cancer Relation, Messina & Wu, Am. J. Clin. Nutr. 2009; 895: 1673S-1679S.

Co-enzyme Q10, Riboflavin and Niacin Supplementation on Alteration of DNA Repair Enzyme and DNA Methylation in Breast Cancer Patients Undergoing Tamoxifen Therapy, Premkumar, Yuvaraj & Sachdanandam, Br. J. Nutr. 2008; 1006: 1179-1182.

Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis, Torti, Pinnix, Miller, at al., Sci. Transl. Med. 2010; 2 (43): 43-56.

Suppression of Proliferation and Invasive Behavior of Human Metastatic Breast Cancer Cells by Dietary Supplement BreastDefend, Wojnowski, Jaing, Jedinak & Sliva, Integr. Cancer Ther. 2010; Oct 6. DOI: 10.1177/1534735410386953.

Vitamin Supplement Use During Breast Cancer Treatment and Survival: A Prospective Cohort Study, Nechuta, Wei Lu, Zhi Chen, et al., Cancer Epidemiol Biomarkers Prev. Published online first December 21, 2010. doi:10.1158/1055-9965.EPI-10-1072.  Vitamin Supplements Beneficial in Patients With Breast Cancer, Nelson, www.medscape.com/viewarticle/735088

Enzyme Therapy in the Treatment of Lymphedema in the Arm After Breast Carcinoma Surgery, Adamek, Prausova, Wald, Chirurgicka Klinika FN Motol, Praha. Rozhl Chir. 1997; 76 (4): 203-204. [Article in Czech].

A Series of Case Reports: Clinical Evaluation of a Complex Homeopathic Injection Therapy in the Management of Pain in Patients After Breast Cancer Treatment, Orellana, Ruiz de Viñaspre & Kaszkin-Bettag, Altern. Ther. Health Med. 2010; 16 (1): 54-59.

BUTYRATE

Sodium Butyrate Inhibits Cell Growth and Stimulates P21 Protein in Human Colonic Adenocarcimoma Cells Independently of P53 Status, Kobayashi, Tan & Fleming, Nutr. & Cancer  2003; 46 (2): 202-211.

Butyrate Induces Glutathione S-Transferase in Human Colon Cells and Protects from Genetic Damage by 4-Hydroxy-2-Nonenal,  Ebert, et al.,  Nutr. & Cancer 2001; 41 (1): 156-164.

Topical Butyrate for Acute Radiation Proctitis: Randomised, Cross-over Trial, Vernia, Fracasso, Casale, et al.,  Lancet  2000; 356 (9237): 1232-1235.

CHINESE MEDICINE (TCM) HERBS & ACUPUNCTURE

Traditional Chinese Medicine In Cancer Symposium, Vanc. Gen. Hosp. Sept. 21, 2003

Astragalus-based Chinese Herbs and Platinum-based Chemotherapy for Advanced Non-small-cell Lung Cancer: Meta-analysis of Randomized Trials, McCulloch, See, Shu, et al., J. Clin. Oncol. 2006; 24 (3): 419-430.

Traditional Chinese Medicine Astragalus Reverses Predominance of Th2 Cytokines and Their Up-stream Transcript Factors in Lung Cancer Patients, Wei, Sun, Xiao, et al., Oncol. Rep. 2003; 10 (5): 1507-1512

Shi-Quan-Da-Bu-Tang (Ten Significant Tonic Decoction), SQT. A Potent Chinese Biological Response Modifier in Cancer Immunotherapy, Potentiation and Detoxification of Anticancer Drugs, Zee-Cheng, Meth. Find. Exp. Clin. Pharmacol. 1992; 14 (9): 725-736.

A Phase II Study of an Herbal Decoction That Includes Astragali Radix for Cancer-Associated Anorexia in Patients with Advanced Cancer, Lee & Lee,  Integr. Cancer Ther. 2010;  9 (1): 24-31.

Immunotherapy with Chinese Medicinal Herbs. I. Immune Restoration of Local Xenogeneic Graft-versus-host Reaction in Cancer Patients by Fractionated Astragalus membranaceus in vitro, Chu, Wong & Mavligit,  J. Clin. Lab. Immunol. 1988; (3): 119-123.

Clinical Study on Effect of Astragalus in Efficacy Enhancing and Toxicity Reducing of Chemotherapy in Patients of Malignant Tumor, Duan & Wang, Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002; 22 (7): 515-517.

Effect of Astragalus Polysaccharides in Promoting Neutrophil-Vascular Endothelial Cell Adhesion and Expression of Related Adhesive Molecules, Hao, Qiu & Wu, Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004; 24 (5): 427-430.

The Radioprotective Effects of Bu-Zhong-Yi-Qi-Tang: A Prescription of Traditional Chinese Medicine Astragalus, Kim, Lee, Oh, et al.  J. Chin. Med. 2002; 30 (1): 127-137.

A Study on the Immune Receptors for Polysaccharides from the Roots of Astragalus membranaceus, a Chinese Medicinal Herb, Shao, Xu, Dai, et al. Biochem. Biophys. Res. Commun. 2004; 320 (4): 1103-1111.

Chinese Medical Herbs for Chemotherapy Side-effects on Colorectal Cancer Patients, Taixiang, Munro & Guanjian, Cochrane Database Syst. Rev. 2005; (1): CD004540.

Cohort Study on the Effect of  a Combined Treatment of Traditional Chinese Medicine and Western Medicine on the Relapse and Metastasis of 222 Patients with Stage II and III Colorectal Cancer After Radical Operation,  Yang, Ge, Wu, et al., Chin. J. Integr. Med. 2008; 144: 251-256.

Clinical Observation on Treatment of Colonic Cancer with Combined Treatment of Chemotherapy and Chinese Herbal Medicine, Zhou, Shan & You, Chin. J. Integr. Med. 2009; 152: 107-111.

Immune System Effects of Echinacea, Ginseng and Astragalus: A Review, Block & Mead,  Integr. Cancer Ther. 2003; 2 (3): 247-267.

Chinese Medicinal Herbs Reverse Macrophage Suppression Induced by Urological Tumors, Rittenhouse, Lui & Lau,  J. Urol. 1991; 146 (2): 486-490.

Integrating Chinese & Conventional Medicine in Colorectal Cancer Treatment, Lahans, Integr. Cancer Ther.  2007; 6 (1): 89-94.

Chinese Herbal Medicine and Chemotherapy in the Treatment of Hepatocellular Carcinoma: A Meta-analysis of Randomized Controlled Trials, Shu, McCulloch, Xiao, et al., Integr. Cancer Ther. 2005; 4 (3): 219-229.

Traditional  Chinese Medicine Herbal Treatment May Have a Relevant Impact on the Prognosis of Patients with Stage IV Adenocarcinoma of the Lung Treated with Platinum-Based  Chemotherapy or Combined Targeted Therapy and Chemotherapy, Guo, Liu, Xu, et al., Integr. Cancer Ther.  2011; 10 (2): 127-137.

“And What Other Medications Are You Taking?” , Gordan, Chay, Kelly, et al., J. Clin. Oncol. 2011: 29 (11): 288-291.  {Reishi for primary liver HCC}

Chinese Herbal Medicine for Cancer Pain, Xu, Lao, Ge, et al., Integr. Cancer Ther. 2007; 6 (3): 208-234.

Cancer Chemo-preventative and Therapeutic Activities of Red Ginseng, Xiaoguang, Hongyan, Xiaohong, et al., J. Ethnopharmacol.  1998; 60 (1): 71-78.

Current Evaluation of the Millennium Phytomedicine- Ginseng (II): Collected Chemical Entities, Modern Pharmacology, and Clinical Applications Emanated from Traditional Chinese Medicine, Jia, Zhao & Liang, Curr. Med. Chem. 2009; 16 (22): 2924-2942.

Sensitization of a Tumor, But Not Normal Tissue, to the Cytotoxic Effect of Ionizing Radiation Using Panax Notoginseng  Extract, Chen ,Wu,  Wang , et al., Am. J. Chin. Med. 2001; 29 (3-4): 517-524.

Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent, Fried & Arbiser, Antioxid. Redox Signal. 2009; 11 (5): 1139–1148.

The Effects of P6 Acupressure in the Prophylaxis of Chemotherapy-Related Nausea and Vomiting in Breast Cancer Patients, Molassiotis, Helin, Dabbour, et al., Complement. Ther. Med. 2007; 15 (1): 3-12.

Acupuncture: Role in Comprehensive Cancer Care – A Primer for the Oncologist and Review of the Literature, Cohen, Menter & Hale, Integr. Cancer Ther. 2005; 4 (2): 131-143.

Acupuncture as Palliative Therapy for Physical Symptoms and Quality of Life for Advanced Cancer Patients, Dean-Clower, Doherty-Gilman, Keshaviah, et al., Integr. Cancer Ther. 2010; 9 (2): 158-167.

The Management of Cancer Related Fatigue After Chemotherapy with Acupuncture and Acupressure: A Randomized Controlled Trial, Molassiotis, Sylt & Diggins,  Complement. Ther. Med.  2007; 154: 228-237.

Acupuncture to Alleviate Chemotherapy-induced Nausea and Vomiting in Paediatric Oncology – A Randomized Multicenter Cossover Pilot Trial, Gottschling, Reindl, Meyer, et al., Klin. Paediatr. 2008; 220 (6): 365-370.

Acupuncture for the Treatment of Vasomotor Symptoms in Breast Cancer Patients Receiving Hormone Suppression Treatment, Walker, et al., Int. J. Rad. Oncol. – Biol. – Phys.  2008; Abstract No. 228. Volume 72, Number 1.

Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea or Vomiting, Ezzo, Richardson,Vickers, et al., Cochrane Database Syst. Rev. 2006; 2: CD002285.  DOI:10.1002/14651858. CD002285.pub2.

Cochrane Review Summary for Cancer Nursing: Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea or Vomiting, Konno, Cancer Nurs. 2010; 33 (6): 479-480.

Acupuncture Versus Venlafaxine for the Management of Vasomotor Symptoms in Patients with Hormone Receptor-Positive Breast Cancer: A Randomized Controlled Trial, Walker, Rodrigues, Kohn, et al., J. Clin. Oncol. 2009; Epub ahead of print PMID: 20038728.

Acupuncture in the Rehabilitation of Women After Breast Cancer Surgery- A Case Series, Alem & Gurgel,  Acup. Med. 2008; 262: 86-93.

Monitoring of Neuromuscular Blockade at the P6 Acupuncture Point Reduces the Incidence of  Post-operative Nausea and Vomiting, Arnberger, Stadelmann, Alischer, et al., Anesthesiology 2007; 107 (6): 903-908. 

Clinical Observations on Post-operative Vomiting Treated by Auricular Acupuncture,  Kim, Kim & Kim, Am. J. Chin. Med. 2003; 31 (3): 475-480.

Clinical Uses of P6 Acupuncture Anti-emesis, Dundee & McMillan, Acup.  Electrother. Res. 1990; 15 (3-4): 211-215.

Acupuncture for Nausea and Vomiting: An Update of Clinical and Experimental Studies,  Streitberger, Ezzo & Schneider, Auton. Neurosci. 2006; 129( 1-2): 107-117.

Effect of Acupressure on Nausea and Vomiting Induced by Chemotherapy in Cancer Patients, Gardani, Cerrone, Biella, et al.,  Minerva Med. 2006; 97 (5): 391-394.

Electroacupuncture for Refractory Acute Emesis Caused by Chemotherapy, Choo, Kong, Lim, et al.,  J. Altern. Complement. Med. 2006; 12 (10): 963-969.

Acupuncture-point Stimulation for Chemotherapy-Induced Nausea or Vomiting, Ezzo, Richardson, Vickers, et al., Cochrane Database Syst. Rev. 2006; (2): CD002285.

Effects of Electro-acupuncture on T-cell Subpopulations, NK Activity, Humoral Immunity and Leukocyte Count in Patients Undergoing Chemotherapy, Ye, Liu, Wang & Xu,  J. Trad. Chin. Med. 2007; 271: 19-21.

Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients, a Randomized, Controlled Trial, Hervik  & Mjaland, Breast Cancer Res. Treat. 2009; 1162: 311-316.

Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea or Vomiting,  Ezzo, Richardson, Vickers, et al., Cochrane Database of Systematic Reviews  2006; 2: CD002285.

Acupuncture for Dysphagia After Chemo-radiation Therapy in Head and Neck Cancer: A Case Series Report, Lu, Posner, Wayne, et al., Integr. Cancer Ther. 2010; 9 (3): 284-290.

Acupuncture versus Metoclopramide in the Treatment of Postoperative Gastroparesis Syndrome in Abdominal Surgical Patients: A Randomized Controlled Trial, Sun, Luo, Wu, et al., J. Chin. Integr. Med. 2010; 8 (7): 641.

CO-ENZYME Q10

Coenzyme Q10 Plasma Levels Predict Melanoma Metastasis, Rusciani, et al,  J. Am. Acad. Dermatology, 2006; 54: 234-241. 

Coenzyme Q Differentially Modulates Phospholipid Hydroperoxide Glutathione Peroxidase Gene Expression and Free Radicals Production in Malignant and Non-malignant Prostate Cells, Quiles, Farquharson, Ramirez-Tortosa, et al., Biofactors 2003; 18 (1-4): 265-270.

Clinical Response of Myelodysplastic Syndromes Patients to Treatment with Coenzyme Q10, Galili, Sechman, Cerny, et al., Leuk Res. 2007 J; 31 (1): 19-26.

Coenzyme q10 for Prevention of Anthracycline-induced Cardiotoxicity, Conklin, Integr Cancer Ther. 2005; 4 (2): 110-130.

CoQ10:  Could It Have a Role in Cancer Management?, Hodges, Hertz, Lockwood & Lister,  BioFactors 1999; 9: 365-370.

An Analysis of the Role of Coenzyme Q in Free Radical Generation and As an Antioxidant, Beyer, Biochem. & Cell Biol.1992; 70 (6): 390-403.

The Mode of Action of Lipid-soluble Antioxidants in Biological Membranes. Relationship Between the Effects of Ubiquinol and Vitamin E as Inhibitors of Lipid Peroxidation in Submitochondrial Particles, Ernster, Forsmark  & Nordenbrand,  J. Nutr. Sci. & Vitamin. 1992; Spec No: 548-551.

Improved Survival in Patients with End-Stage Cancer Treated with Coenzyme Q10 and Other Antioxidants, Hertx & Lister, J. Int. Med. Res. 2009; 37: 1961-1971.

CURCUMIN & INFLAMMATION

Curcumin and Green Tea Polyphenols: Synergistic Anticancer Compounds, Yarnell, Quart. Rev. Nat. Med. 1998; Fall: 218-220.

Antioxidant and Anti-inflammatory Properties of Curcumin, Menon & Sudheer, Adv. Exp. Med. Biol. 2007; 595: 105-125.

Curcumin and Resveratrol Inhibit Nuclear Factor-kappaB-mediated Cytokine Expression in Adipocytes, Gonzales & Orlando, Nutr. Metab. (Lond). 2008; 5 (1): 17.

Regulation of COX and LOX by Curcumin, Rao, Adv. Exp. Med. Biol. 2007; 595: 213-226.

Induction of Apoptosis by Curcumin and its Implications for Cancer Therapy, Karunagaran, Rashmi  & Kumar, Curr. Cancer Drug Targets 2005; 5 (2): 117-129.

Biological Effects of Curcumin and its Role in Cancer Chemoprevention and Therapy, Singh & Khar, Anticancer Agents Med.Chem. 2006; 6 (3): 259-270.

Chemotherapeutic Potential of Curcumin for Colorectal Cancer, Chauhan, Curr. Pharm. Des. 2002; 8 (19): 1695-1706.

Curcumin Dually Inhibits Both mTOR and NF-{kappa}B Pathways Through a Crossed PI3K/Akt/IKK Signaling Axis in Adenoid Cystic Carcinoma, Sun, Chen, Zhang, et al., Mol. Pharmacol. 2010; [Epub ahead of print] PMID: 20959361.

Synergistic Inhibitory Effects of Curcumin and 5-FluoroUracil on the Growth of the Human Colon Cancer Cell Line HT-29,  Du, Jiang, Xia & Zhong, Chemotherapy 2006;52 (1): 23-28.

Curcumin Inhibits Human Colon Cancer cell Growth by Suppressing Gene Expression of Epidermal Growth Factor Receptor Through Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu & Johnson, Oncogene 2005; Sept. 19, Epub.

Molecular Targets of Curcumin, Lin, Adv. Exp. Med. Biol. 2007; 595: 227-243.

Curcumin, an Anti-oxidant and Anti-tumor Promoter, Induces Apoptosis in Human Leukemia Cells, Kuo, Huang & Lin,  Biochem Biophys Acta 1996; 131 (7): 95-100.

The Chemopreventive Agent Curcumin is a Potent Radiosensitizer of Human Cervical Tumor Cells via Increased Reactive Oxygen Species Production and Overactivation of the Mitogen-activated Protein Kinase Pathway, Javvadi, Segan, Tuttle & Koumenis,  Mol Pharmacol. 2008 May; 73 (5): 1491-501.

Curcumin, a Dietary Component, has Anti-cancer, Chemo-sensitization, and Radio-sensitization Effects by Down-regulating the MDM2 Oncogene Through the P13K/mTOR/ETS2 Pathway, Zhang, Hill, Wang & Zhang, Cancer Res. 2007; 67 (5): 1988-1996.

Cellular Foundation of Curcumin-induced Apoptosis in Follicular Lymphoma Cell Lines, Skommer, Wlodkowic & Pelkonen, Exp. Hematol. 2006; 34 (4): 463-474.

Curcumin Inhibits Human Colon Cancer Cell Growth by Suppressing Gene Expression of Epidermal Growth Factor Receptor Through Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu  & Johnson, Oncogene 2006; 25: 278-287.

Therapeutic Potential of Curcumin in Human Prostate Cancer-1.  Curcumin Induces Apoptosis in Both Androgen-dependent and Androgen-independent Prostate Cancer Cells,  Dorai, Gehani & Katz,  Prost. Cancer Prost. Dis.  2000; 3: 84-93.

Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer, Somasundaram, Edmund, Moore, et al., Cancer Res.   2002; 62 (13): 3868-3875.

Can a Common Spice be Used to Treat Cancer?, Witter, Oncolog.  2007; 52 (9): 4-5.

Curcumin and Colorectal Cancer: Add Spice to Your Life, Kunnumakarra, Guha &Aggarwal, Curr. Colorect. Cancer Rep. 2009; 5: 5-14.

Curcumin as Chemosensitizer, Limtrakul, Adv. Exp. Med. Biol. 2007; 595: 269-300.

Chemopreventive and Therapeutic Effects of Curcumin [Mini-Review],Duvoix, Blasius, Delhalle, et al., Cancer Letters 2005; 223: 181–190.

Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer, Somasundaram, Edmund, Moore, et al., Cancer Res. 2002; 62 (13): 3868-3875.

Modulation of Function of Three Drug Transporters, P-Glycoprotein (ABCB1), Mitoxantrone Resistance Protein (ABCG2) and Multi-drug Resistance Protein 1 (ABCC1) by Tetrahydrocurcumin, a Major Metabolite of Curcumin, Limtrakul, Chearwae, Shukia, et al., Mol. Cell  Biochem. 2007; 296 (1-2): 85-95.

Aspirin, COX-2 Inhibitors Effective as Adjuvant Therapy in Stage III Colon Cancer, Fuchs, Amer. Soc. Clin. Onc., AGM  May 16, 2005; Abstract 3530, as reported by Schuster, Medscape Medical News, May 2005; article 504976.

Helicobacter Infection, Chronic Inflammation and the Development of Malignancy, Crowe, Curr. Opin. Gastroenterol. 2005; 21 (1): 32-38.

Nutritional and Botanical Modulation of the Inflammatory Cascade – Eicosanoids, Cyclooxygenases and Lipoxygenases – As an Adjunct in Cancer Therapy,  Wallace, Integr. Cancer Ther. 2002; 1 (1): 7-37.

Inflammation, COX-2 Inhibitors, & Cancer, Block, Integr. Cancer Ther. 2005; 4 (1): 3-4.

Inflammation and Cancer: An Ancient Link with Novel Potentials, Perwez Hussain & Harris,  Int. J. Cancer  2007; 121 (11): 2373-2380.

NF-kappaB: A Stress-regulated Switch for Cell Survival, Piva, Belardo & Santoro,  Antioxid. Redox  Signal. 2006; 8 (3-4): 478-486.

Cancer Cachexia and Targeting Chronic Inflammation: A Unified Approach to Cancer Treatment and Palliative/Supportive Care, MacDonald,  J. Support. Oncol. 2007; 5 (4): 157-162.

Inflammation and Cancer, Coussens & Werb, Nature 2002; 420 (6917): 860-867.

Significance and Relationship Between Infiltrating Inflammatory Cell and Tumor Angiogenesis in Hepatocellular Carcinoma Tissues, Peng, Deng, Yang, et al.,  World J Gastroenterol. 2005; 11 (41): 6521-6524.

Inflammatory Cell Infiltration of Tumors: Jekyll or Hyde, Talmadge, Donkor, & Scholar,  Cancer Metastasis Rev. 2007; 26 (3-4): 373- 400.

Bioavailability of Curcumin: Problems and Promises, Anaand, Kunnumakkara, Newman, et al., Molec. Pharm. 2007; 4 (6): 807-818.

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer, Dhillon, Aggarwal, Newman, et al., Clin. Cancer Res. 2008; 14 (14): 4491-4499.

 Inflammation and Prostate Cancer, Vasto, Carruba, Candore, et al., Future Oncol. 2008; 4 (5): 637-645.

Prevention and Treatment of Pancreatic Cancer by Curcumin in Combination with Omega-3 Fatty Acids, Swamy, Citineni, et al, Nutr. Cancer  2008; 60 Suppl. 1: 81-89.

Curcumin Inhibits Human Colon Cancer Cell Growth by Suppressing Gene Expression of Epidermal Growth Factor Receptor Through Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu & Johnson, Oncogene 2006; 25 (2): 278-287.

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer, Dhillon, Aggarwal, Newman, et al., Clin. Cancer Res. 2008; 14 (14): 4491-4499.

Inhibitory Effect of Curcumin, a Food Spice from Turmeric, on Platelet-activating Factor and Arachidonic Acid-mediated Platelet Aggregation Through Inhibition of Thromboxane Formation and Ca2+ Signalling, Shah, Nawaz, Pertani, et al., Biochem. Pharmacol. 1999; 58 (7): 1167-1172.

Combination Treatment with Curcumin and Quercetin of Adenomas in Familial Adenomatous Polyposis, Cruz-Correa, Shoskes, Sanchez, et al., Clin. Gastroenterol. Hepatol. 2006; 4 (8): 1035-1038.

Curcumin Inhibits Proliferation, Invasion, Angiogenesis and Metastasis of Different Cancers Through Interaction with Multiple Cell Signaling Proteins, Kunnumakkara, Anand &Aggarwal, Cancer Lett. 2008;[Epub ahead of print].

Curcumin (Diferuloylmethane) Down-regulates Expression of Cell Proliferation and Anti-apoptotic and Metastatic Gene Products Through Suppression of I-kappaB-alpha Kinase and Akt Activation, Aggarwal, Ichikawa, Takada, et al., Mol. Pharmacol. 2006; 69 (1): 195-206.

Curcumin Down-Regulates the Multidrug-resistance Mdr1b Gene by Inhibiting the PI3K/Akt/NF kappa B Pathway, Choi, Kim, Lim, et al., Cancer Lett. 2008; 259 (1): 111-118.

Amelioration of Immune Cell number Depletion and Potentiation of Depressed Detoxification System of Tumor-bearing Mice by Curcumin, Pal, Bhattacharyya, Choudhuri, et al., Cancer Detect. Prev. 2005; 29 (5): 470-478

Vitamin Antioxidants, Lipid Peroxidation, Tumour Stage, the Systemic Inflammatory Response and Survival in Patients with Colorectal Cancer, Leung, Crozier, Talwar, et al., Int. J. Cancer  2008; 12310: 2460-2464.

Evaluation of Anti-inflammatory Property of Curcumin (diferuloyl methane) in Patients with Postoperative Inflammation, Satoskar, Shah & Shenoy,   Int. J. Clin. Pharmacol. Ther. Toxicol. 1986; 24: 651-654.

Biological Effects of Curcumin and its Role in Cancer Chemoprevention and Therapy, Singh & Khar,  Anticancer Agents Med. Chem. 2006; 6 (3): 259-270.

Chemotherapeutic Potential of Curcumin for Colorectal Cancer, Chauhan, Curr. Pharm. Des. 2002; 8 (19): 1695-1706

Suppression of the Nuclear Factor-kappaB Activation Pathway by Spice-derived Phytochemicals: Reasoning for Seasoning, Aggarwal & Shishodia, Ann. N. Y. Acad. Sci. 2004; 1030: 434-441.

Phase I Dose Escalation Trial of Docetaxol Plus Curcumin in Patients with Advanced and Metastatic Breast Cancer, Bayet-Robert, Kwiatkowski, Leheurteur, et al., Cancer Biol. Ther. 2010, 9 (1): [Epub ahead of print}. PMID 19901561.

Curcumin in Combination with Bortezomib Synergistically Induced Apoptosis in Human Multiple Myeloma U266 Cells, Park, Ayyappan, Bae, et al., Molecular Oncology 2009 2 (4): 317-326.

Curcumin Circumvents Chemoresistance in vitro and Potentiates the Effect of Thalidomide and Bortezomib Against Human Multiple Myeloma in Nude Mice Model, Sung, Kunnumakkara, Sethi, et al., Mol. Cancer Ther. 2009; 8 (4): 959-970.

Curcumin as an Anti-cancer Agent: Review of the Gap Between Basic and Clinical Applications, Bar-Sela, Epelbaum & Schaffer, Curr. Med. Chem. 2010; 17 (3): 190-197(8).

Aromatase Inhibitor Letrozole in Synergy with Curcumin in the Inhibition of Xenografted Endometrial Carcinoma Growth, Liang, Hao, Wu, et al., Int. J. Gynecol. Cancer 2009; 19 (7): 1248-1252.

Curcumin Inhibits Prosurvival Pathways in Chronic Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in Combination with EGCG, Ghosh, Kay, Secreto & Shanafelt, Clin. Cancer Res. 2009; 15 (4): 1250-1258.

Elimination of Colon Cancer Stem-like Cells by the Combination of Curcumin and FOLFOX, Yu, Kanwar, Patel, et al., Transl. Oncol. 2009; 2 (4): 321-328.

Curcuma wenyujin Extract Induces Apoptosis and Inhibits Proliferation of Human Cervical Cancer Cells in Vitro and in Vivo, Lim, Ky, Ng, et al., Integr. Cancer Ther. 2010; 9 (1): 36-49.

Phase I/II Study of Gemcitabine-based Chemotherapy Plus Curcumin for Patients with Gemcitabine-resistant

Pancreatic Cancer, Kanai, Yoshimura, Asada, et al., Cancer Chemother. Pharmacol.  2010;  published online Sept. 22, 2010:  DOI 10.1007/s00280-010-1470-2A.

Comparison of Systemic Availability of Curcumin with that of Curcumin Formulated with Phosphatidylcholine, Marczylo, Verschoyle, Cooke, et al., Cancer Chemother. Pharmacol.  2007; 60 (2):171-177.

Curcumin Inhibits GPVI-Mediated Platelet Activation by Interfering with the Kinase activity of Syk and the Subsequent Activation of PLCgamma2, Mayanglambam, Dangelmaier, Thomas, et al., Platelets 2010; 21 (3): 211-220.

Curcumin Dually Inhibits Both mTOR and NF-{kappa}B Pathways Through a Crossed PI3K/Akt/IKK Signaling Axis in Adenoid Cystic Carcinoma, Sun, Chen, Zhang, et al., Mol. Pharmacol. 2010; [Epub ahead of print] PMID: 20959361.

Curcumin: A Novel Nutritionally Derived Ligand of the Vitamin D Receptor with Implications for Colon Cancer Chemoprevention, Bartika, Whitfielda, Kaczmarskaa, et al., J. Nutr. Biochem. 2010; 21: 1153–1161.

Novel STAT3 Phosphorylation Inhibitors [from Curcumin ]Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells, Lin, Hutzen, Zuo, et al., Cancer Res. 2010; 70 (6): 2445-2454.

Protective Effect of Curcumin in Cisplatin-Induced Oxidative Injury in Rat Testis: Mitogen-Activated Protein Kinase and Nuclear Factor-kappa B Signaling Pathways,  Ilbey, Ozbek, Cekmen, et al., Human Reproduction 2009; 24 (7): 1717–1725.

Curcumin Inhibits Pro-survival Pathways in Chronic Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in Combination with EGCG, Ghosh, Kay, Secreto & Shanafelt, Clin. Cancer Res. 2009; 15 (4): 1250-1258.

Curcumin Induces Downregulation of E2F4 Expression and Apoptotic Cell Death in HCT1116 Human Colon Cancr Cells: Involvement of Reactive Oxygen Species, Kim & Lee, Korean J. Physiol. Pharmacol. 2010; 14 (6): 391-397.

Curcumin in Cancer Chemoprevention: Molecular Targets, Pharmacokinetics,Bioavailability, and Clinical Trials, Shehzad, Wahid & Lee, Arch. Pharm. (Weinheim). 2010; 343 (9): 489-499.

Pharmacokinetics and Pharmacodynamics of  Curcumin. Sharma, Steward & Gescher, Adv. Exp. Med. Biol. 2007; 595: 453-470.

Curcumin Suppresses Human Papillomavirus Oncoproteins, Restores p53, Rb, and PTPN13 Proteins and Inhibits Benzo[a]pyrene-induced Upregulation of HPV E7, Maher, Bell, O'Donnell, et al., Mol. Carcinog. 2011; 50 (1): 47-57.   

Curcumin Counteracts the Proliferative Effect of Estradiol and Induces Apoptosis in Cervical Cancer Cells, Singh & Singh, Mol. Cell Biochem. 2011; 347 (1-2):1-11.

Molecular Mechanism of Curcumin Induced Cytotoxicity in Human Cervical Carcinoma Cells, Singh & Singh, Mol. Cell Biochem. 2009; 325 (1-2):107-119.

Upregulation of p53 Expression in Patients with Colorectal Cancer by Administration of Curcumin, He, Shi, Wen, et al., Cancer Inv. 2011; 29: 208–213.

Regression of Follicular Lymphoma with Devil’s Claw: Coincidence or Causation?, Wilson, Curr. Oncol. 2009; 16 (4): 67-70.

DIET & GENERAL INTEGRATIVE ONCOLOGY

Natural Health Products and Cancer Treatment, Hal Gunn, Complementary Corner, Summer 2003 Vol. 4 No. 3 www.abreastinthewest.ca   (BCCA policy re: natural agents)

Multivitamin Use and Breast Cancer Incidence in a Prospective Cohort of Swedish Women, Laarson, Akesson, Bergkvist & Wolk,  Am. J. Clin. Nutr. 2010; 91 (5): 1268-1272.

Use of Complementary / Integrative Nutritional Therapies During Cancer Treatment: Implications in Clinical Practice,  Kumar et al.,  Canc. Control  2002; 9 (3): 236-243.

Complementary Therapies for Cancer-related Symptoms, Deng, Cassileth & Yeung, J. Support Oncol. 2004; 2: 419-429.

Complementary and Alternative Therapies for Cancer, Cassileth & Deng, Oncologist 2004; 9: 80-89.

Integrative Oncology: Complementary Therapies in Cancer Care, Cassileth, Heitzer & Gubili, Cancer Chemother. Rev. 2008; 3 (4): 204-211.

Lifestyle changes and the ‘spontaneous’ regression of cancer: An initial computer analysis  Foster, Int. J. Biosoc. Res., 1988; 10 (1): 17-33.

Exercise in Prevention and Management of Cancer, Newton & Galvao, Curr. Treat. Opt. Oncol. 2008; 92 (3): 135-146.

Forgiveness Can Improve Immune Function, Owen, Soc. Behav. Med. 32nd Annual Meeting and Scientific Sessions: Abstract 4010. Presented April 30, 2011.

Molecular Targets of Dietary Agents for Prevention and Therapy of Cancer, Aggarwal & Shishodia, Biochem. Pharmacol. 2006; 71: (10): 1397-1421.

Analysis of Botanicals and Dietary Supplements for Antioxidant Capacity: a Review,  Prior & Cao,  J. AOAC Int. 2000; 83 (4): 950-956.

(Gamma)ɣ-Tocopherol Traps Mutagenic Electrophiles Such As NOx and Complements (Alpha)α-Tocopherol: Physiological Implications, Christen, Woodall, Shigenaga, et al., Proc. Natl. Acad. Sci. 1997; 94: 3217-3222.

Dietary Fat, Fiber, Vegetable, and Micronutrients are Associated with Overall Survival in Postmenopausal Women Diagnosed with Breast Cancer, McEligot, Largent, Ziogas, Peel & Anton-Culver,  Nutr. Cancer. 2006; 55 (2): 132-140.

Dietary Influences on Survival After Ovarian Cancer, Nagle, Purdie, Webb, et al., Int. J. Cancer 2003; 106 (2): 264-269.

Association of Dietary Patterns with Cancer Recurrence and Survival in Patients with Stage III Colon Cancer, Meyerhardt , Niedzwiecki , Hollis, et al., J. Amer. Med. Assoc.  2007; 298 (7):754 -764.

Greater Survival After Breast Cancer in Physically Active Women with High Vegetable-Fruit Intake Regardless of Obesity, Pierce, Stefanick, Flatt, et al., J. Clin. Oncol. 2007; 25 (17): 2345-2351.

Influence of a Diet Very High in Vegetables, Fruit and Fiber and Low in Fat on Prognosis Following Treatment for Breast Cancer, J. Amer. Med. Assoc. 2007; 298 (3): 289-298.

Baseline Nutritional Status is Predictive of Response to Treatment and Survival in Patients treated by Definitive Chemo-Radiotherapy for a Locally Advanced Esophageal Cancer, Di Fiore, Lecleire, Pop, et al., Am. J. Gastroenterol. 2007; 102 (11): 2557-2563.

Is Voluntary Vitamin and Mineral Supplementation Associated with Better Outcome in Non-Small Cell Lung Cancer Patients? Results from the Mayo Clinic Lung Cancer Cohort. Jatoi, Williams, Nichols, et al.,   Lung Cancer. 2005; 49 (1): 77-84.

Cancer and Natural Medicine – a Textbook of Basic Science and Clinical Research , John Boik, 1996 Oregon Medical Press.

Naturally There’s Hope – A Handbook for the Naturopathic Care of Cancer Patients, McKinney, Trafford Press, 2003.

Survival Impact of Integrative Cancer Care in Advanced Metastatic Breast Cancer,  Block, Gyllenhaal, Tripathy, et al., In press, The Breast Journal 2009; 15 (4).

Survival Impact of Integrative Care in Advanced Prostate Cancer, Block, Gyllenhaal, Chodak, et al., Proc. Am. Soc. Clin. Oncol. 2003; 22: abstract 1746.

Mind-body Therapies for the Management of Pain, Astin, Clin. J. Pain 2004; 20 (1): 27-32.

Pilot Crossover Trial of Reiki vs. Rest for Treating Cancer-related Fatigue, Tsang, Carlson & Olson, Integr. Cancer Ther. 2007; 6 (1): 25-35.

Efficacy of Homeopathic Therapy in Cancer Treatment,  Milazzo, Russell & Ernst,  Eur. J. Cancer, 2006; 42 : 282-289.

Effect of Homeopathic Medicines on Transplanted Tumors in Mice, Sunila, Kuttan, Preethi & Kuttan, Asian Pac. J. Cancer Prev. 2007; 8: 390-394.

Series of Case Reports: Clinical Evaluation of a Complex Homeopathic Injection Therapy in the Management of Pain in Patients After Breast Cancer Treatment, Orellana, Ruiz de Viñaspre & Kaszkin-Bettag, Altern. Ther. Health Med. 2010; 16 (1): 54-59.

Cytotoxic Effects of Ultra-diluted Remedies on Breast Cancer Cells, Frenkel, Mishra, Sen, et al.,  Int. J. Oncol. 2010; 36 (2): 395-403.  PMID: 20043074

The Effect of Thiamine Supplementation on Tumour Proliferation: A Metabolic Control Analysis Study,

ComõÂn-Anduix, Boren, Martinez, et al., Eur. J. Biochem. 2001; 268: 4177- 4182.

The Hoxsey Treatment: Cancer Quackery or Effective Physiological Adjuvant?, Brinker,  J. Naturopathic Med. 1996; 6(1): 9-23.

Broad in vitro Efficacy of Plant-derived Betulinic Acid Against Cell Lines Derived from the Most Prevalent Human Cancer Types, Kessler, Mullauer, dee Roo & Medema, Cancer Lett. 2007; 251 (1): 132-145                                                              

Complementary & Alternative Medicine, Larson, Trustee Mag. 2006, Sept.

Survival Impact of Integrative Care in Advanced Prostate Cancer, Block, Gyllenhaal, Chodak et al.,  Proc. Am Soc Clin Oncol. 2003; 22: abstract 1746.

Survival Impact of Integrative Cancer Care in Advanced Metastatic Breast Cancer, Block, Gyllenhaal, Tripathy et al., The Breast Journal. 2008; in press.

Natural Compounds in Cancer Therapy – Promising Non-toxic Anti-tumor Agents from Plants and Other Natural Sources, John Boik, Oregon Medical Press  2001.