Hubungi sekarang juga - Kami mengerjakan tugas kuliah kedokteran
, makalah, paper, proposal skripsi, tugas akhir, dijamin orisinil dan otentik. 0812 1944 9060
Jurnal yang sering digunakan untuk penelitian kedokteran:
• Cancer
• Nutrition
& Cancer
• Journal
of Clinical Oncology
• Journal
of the National Cancer Institute
• Cancer
Research
• Integrative
Cancer Therapies
• American
Journal of Clinical Nutrition
• Alternative
Medicine Review
• International
Journal of Cancer
• Clinical
Pearls
• Anticancer
Research
• Townsend
Letter for Doctors & Their Patients
WEB RESOURCES
• www.oncanp.org
• www.aicr.org
• www.lifeovercancer.com
• www.cancerfacts.com
• www.nci.nih.gov
• www.cancernet.nci.nih.gov/clinpdq
• www.cancer.org American Cancer Society 1-800-ACS-2345
• www.cdc.gov.org/cancer
• www.bccancer.bc.ca
• www.y-me.org
• www.asco.org
• www.Medscape.com - oncology database
• www.inspirehealth.ca
• www.denvernaturopathic.com
• www.camresearch.net
• www.ncbi.nlm.nih.gov/PubMed/
• www.oncologystat.com
• www.epec.net
• www.lifeovercancer.com
Topic penelitian yang sedang menarik yang dapat anda gunakan
untuk diteliti:
Antitumor and Radiosensitizing Effects of Withania somnifera
(Ashwagandha) on a Transplantable Mouse Tumor, Sarcoma -180. Devi & Solomon Ind. J. Exp. Biol. July 1993; 31 (7):
607-611.
In vivo Growth Inhibitory Effect of Withania somnifera (
Ashwagandha) on a Transplantable Mouse Tumor Sarcoma-180, Devi, Sharada,
Solomon, et al., Ind. J. Exp. Biol. 1992; 30: 169-172.
Withania somnifera dunal: Potential Plant Source of a
Promising Drug for Chemotherapy and Radiosensitization, Devi, Ind. J. Exp.
Biol. 1996; 34 (10): 927-932.
In vivo growth Inhibitory and Radiosensitizing Effects of
Withaferin A on Mouse Erlich Ascites Carcinoma in vivo, Devi, Sharada &
Solomon, Acat. Oncol. 1996; 35: 95-100.
Modulation of TCA Cycle Enzymes and Electron Transport Chain
Systems (by Withania) In Experimental Lung Cancer, Senhilnathan, Padmavathi,
Magesh & Sakthisekaran, Life Sci. 2006; 78 (9): 1010-1014.
Immunoprotection by Botanical Drugs in Cancer Chemotherapy,
Diwanay, Chitre & Patwardhan, J.
Ethnopharmacol. 2004; 90 (1): 49-55
The Protective Effect of a Purified Extract of Withania
somnifera Against Doxorubicin-induced Cardiac Toxicity in Rats, Hamza, Amin
& Daoud, Cell Biol. Toxicol. 2008;
24 (1): 63-73.
Enhancement of the Response of B16F1 |Melanoma to
Fractionated Radiotherapy and Prolongation of Survival by Withaferin and/or
Hyperthermia, Kalthur & Pathirissery, Integr. Cancer Ther. 2010; 9 (4):
370-377.
AVEMAR
Fermented Wheat Germ Extract (Avemar) in the Treatment of
Cancer and Autoimmune Diseases, Boros, Nichelatti & Shoenfeld, Ann. N.Y.
Acad. Sci. 2005; 1051: 529-542.
Antimetastatic Effect of Avemar in High-risk Melanoma
Patients, Demidov, Manzjuk, Kharkevitch, et. al., 18th UICC International Cancer
Congress, 2002; P868 - Oslo, Norway.
Adjuvant Fermented Wheat Germ Extract (Avemar) Nutraceutical
Improves Survival of High-Risk Melanoma Patients: A Randomized, Pilot, Phase II
Clinical Study with a 7-Year Follow-Up, Demidov, Manzuik, Kharkevitch, et al.,
Cancer Biother. Radiopharm. 2008; 23 (4): 477-482.
A Medical Nutriment Has Supportive Value in the Treament of
Colorectal Cancer, Jakab, Schoenfeld, Balogh, et al., Br. J. Cancer 2003; 89
(3): 465-469.
Fermented Wheat Germ Extract Reduces Chemotherapy-Induced
Febrile Neutropenia in Pediatric Cancer Patients, Garami, Schuler, Babosa, et
al., J. Pediatr. Hematol. Oncol. 2004; 26 (10): 631–635.
Promising Cytotoxic Activity Profile of Fermented Wheat Germ
Extract (Avemar®) in Human Cancer Cell Lines, Mueller, Jordan & Voigt, J.
Exp. Clin. Cancer Res. 2011; 30: 42.
BOSWELLIA
Analysis of Frankincense from Various Boswellia Species with
Inhibitory Activity on Human Drug Metabolising Cytochrome P450 Enzymes Using
Liquid Chromatography Mass Spectrometry After Automated On-line Extraction,
Frank & Unger, J. Chromatogr. A. 2006; 1112 (1-2): 255-262.
Boswellic Acids and Malignant Glioma: Induction of Apoptosis
but No Modulation of Drug Sensitivity, Glaser, Winters, Groscurth, et. al., Br.
J. Cancer 1998; 80 (5-6): 756-765.
Boswellic Acids Inhibit Glioma Growth: A New Treatment
Option?, Winking, Sarikaya, et. al., J. Neurooncol 2000; 46: 97-103.
Boswellic Acids in the Palliative Therapy of Children with
Progressive or Relapsed Brain Tumors, Janssen, Bode, Breu, et. al., Klin.
Paediatr. 2000; 212: 189-195.
Response of Radio-Chemotherapy-associated Cerebral Edema to
a Phytotherapeutic Agent H15, Streffer, Bitzer, Schabet, et al., Neurology
2001; 56: 1219-1221.
Boswellic Acid Acetate Induces Differentiation and Apoptosis
in Leukemia Cell Lines, Jing, Nakato, et al., Leuk. Res. 1999; 23: 43-50.
Boswellic Acids: Novel, Specific, Non-redox Inhibitors of
5-lipoxygenase, Safayhi, Mack, Sabieraj, et al., J. Pharmacol. Exp. Ther. 1992;
261 (3): 1143-1146.
[Boswellia] A Lipoxygenase Inhibitor in Breast Cancer Brain
Metastases, Flavin, J. Neurooncol. 2007; 82 (1): 91-93. Epub 2006 Sep 26.
BREAST CANCER
Survival Impact of Integrative Cancer Care in Advanced
Metastatic Breast Cancer, Block, Gyllenhaal, Tripathy, et al., Breast J. 2009;
154: 357-366.
Apparent Partial Remission of Breast Cancer in “High-Risk”
Patients Supplemented with Nutritional Antioxidants, Essential fatty acids and
Coenzyme Q10, Lockwood, Moesgaard,
Hanioka, et. al., Mol. Aspects. Med. 1994; Suppl. 15: 231-240.
Progress on Therapy of Breast Cancer with Vitamin Q10 and
the Regression of Metastases, Lockwood, Moesgaard, Yamamoto & Folkers,
Biochem. Biophys. Res. Commun. 1995; 212 (1): 172-177.
The Israeli Breast Cancer Anomaly, Westin & Richter,
Annals N.Y. Acad. Sci. 1989; 609:
269-279.
Alteration of the Effects of Cancer Therapy Agents on Breast
Cancer Cells by the Herbal Medicine Black Cohosh, Rockwewll, Liu & Higgins,
Breast Cancer Res. Treat. 2005; 90: 233-239.
Fibroblasts Isolated from Common Sites of Breast Cancer
Metastasis Enhance Cancer Cell Growth Rates and Invasiveness in an
Interleukin-6-Dependent Manner, Studebaker, Storci, Werbeck, et al., Cancer
Res. 2008; 68 (21): 9087-9095.
Psychologic Intervention Improves Survival for Breast Cancer
Patients: A Randomized Clinical Trial, Andersen, Yang, Farrar, et al., Cancer
2008; 113:3450-3458.
Perspectives on the Soy-Breast Cancer Relation, Messina
& Wu, Am. J. Clin. Nutr. 2009; 895: 1673S-1679S.
Co-enzyme Q10, Riboflavin and Niacin Supplementation on
Alteration of DNA Repair Enzyme and DNA Methylation in Breast Cancer Patients
Undergoing Tamoxifen Therapy, Premkumar, Yuvaraj & Sachdanandam, Br. J.
Nutr. 2008; 1006: 1179-1182.
Ferroportin and Iron Regulation in Breast Cancer Progression
and Prognosis, Torti, Pinnix, Miller, at al., Sci. Transl. Med. 2010; 2 (43):
43-56.
Suppression of Proliferation and Invasive Behavior of Human
Metastatic Breast Cancer Cells by Dietary Supplement BreastDefend, Wojnowski,
Jaing, Jedinak & Sliva, Integr. Cancer Ther. 2010; Oct 6. DOI:
10.1177/1534735410386953.
Vitamin Supplement Use During Breast Cancer Treatment and
Survival: A Prospective Cohort Study, Nechuta, Wei Lu, Zhi Chen, et al., Cancer
Epidemiol Biomarkers Prev. Published online first December 21, 2010.
doi:10.1158/1055-9965.EPI-10-1072.
Vitamin Supplements Beneficial in Patients With Breast Cancer, Nelson,
www.medscape.com/viewarticle/735088
Enzyme Therapy in the Treatment of Lymphedema in the Arm
After Breast Carcinoma Surgery, Adamek, Prausova, Wald, Chirurgicka Klinika FN
Motol, Praha. Rozhl Chir. 1997; 76 (4): 203-204. [Article in Czech].
A Series of Case Reports: Clinical Evaluation of a Complex
Homeopathic Injection Therapy in the Management of Pain in Patients After
Breast Cancer Treatment, Orellana, Ruiz de ViƱaspre & Kaszkin-Bettag,
Altern. Ther. Health Med. 2010; 16 (1): 54-59.
BUTYRATE
Sodium Butyrate Inhibits Cell Growth and Stimulates P21
Protein in Human Colonic Adenocarcimoma Cells Independently of P53 Status,
Kobayashi, Tan & Fleming, Nutr. & Cancer 2003; 46 (2): 202-211.
Butyrate Induces Glutathione S-Transferase in Human Colon
Cells and Protects from Genetic Damage by 4-Hydroxy-2-Nonenal, Ebert, et al., Nutr. & Cancer 2001; 41 (1): 156-164.
Topical Butyrate for Acute Radiation Proctitis: Randomised,
Cross-over Trial, Vernia, Fracasso, Casale, et al., Lancet
2000; 356 (9237): 1232-1235.
CHINESE MEDICINE (TCM) HERBS & ACUPUNCTURE
Traditional Chinese Medicine In Cancer Symposium, Vanc. Gen.
Hosp. Sept. 21, 2003
Astragalus-based Chinese Herbs and Platinum-based
Chemotherapy for Advanced Non-small-cell Lung Cancer: Meta-analysis of
Randomized Trials, McCulloch, See, Shu, et al., J. Clin. Oncol. 2006; 24 (3):
419-430.
Traditional Chinese Medicine Astragalus Reverses
Predominance of Th2 Cytokines and Their Up-stream Transcript Factors in Lung
Cancer Patients, Wei, Sun, Xiao, et al., Oncol. Rep. 2003; 10 (5): 1507-1512
Shi-Quan-Da-Bu-Tang (Ten Significant Tonic Decoction), SQT.
A Potent Chinese Biological Response Modifier in Cancer Immunotherapy,
Potentiation and Detoxification of Anticancer Drugs, Zee-Cheng, Meth. Find. Exp.
Clin. Pharmacol. 1992; 14 (9): 725-736.
A Phase II Study of an Herbal Decoction That Includes
Astragali Radix for Cancer-Associated Anorexia in Patients with Advanced
Cancer, Lee & Lee, Integr. Cancer
Ther. 2010; 9 (1): 24-31.
Immunotherapy with Chinese Medicinal Herbs. I. Immune
Restoration of Local Xenogeneic Graft-versus-host Reaction in Cancer Patients
by Fractionated Astragalus membranaceus in vitro, Chu, Wong &
Mavligit, J. Clin. Lab. Immunol. 1988;
(3): 119-123.
Clinical Study on Effect of Astragalus in Efficacy Enhancing
and Toxicity Reducing of Chemotherapy in Patients of Malignant Tumor, Duan
& Wang, Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002; 22 (7): 515-517.
Effect of Astragalus Polysaccharides in Promoting
Neutrophil-Vascular Endothelial Cell Adhesion and Expression of Related
Adhesive Molecules, Hao, Qiu & Wu, Zhongguo Zhong Xi Yi Jie He Za Zhi.
2004; 24 (5): 427-430.
The Radioprotective Effects of Bu-Zhong-Yi-Qi-Tang: A
Prescription of Traditional Chinese Medicine Astragalus, Kim, Lee, Oh, et
al. J. Chin. Med. 2002; 30 (1): 127-137.
A Study on the Immune Receptors for Polysaccharides from the
Roots of Astragalus membranaceus, a Chinese Medicinal Herb, Shao, Xu, Dai, et
al. Biochem. Biophys. Res. Commun. 2004; 320 (4): 1103-1111.
Chinese Medical Herbs for Chemotherapy Side-effects on
Colorectal Cancer Patients, Taixiang, Munro & Guanjian, Cochrane Database
Syst. Rev. 2005; (1): CD004540.
Cohort Study on the Effect of a Combined Treatment of Traditional Chinese
Medicine and Western Medicine on the Relapse and Metastasis of 222 Patients
with Stage II and III Colorectal Cancer After Radical Operation, Yang, Ge, Wu, et al., Chin. J. Integr. Med.
2008; 144: 251-256.
Clinical Observation on Treatment of Colonic Cancer with
Combined Treatment of Chemotherapy and Chinese Herbal Medicine, Zhou, Shan
& You, Chin. J. Integr. Med. 2009; 152: 107-111.
Immune System Effects of Echinacea, Ginseng and Astragalus:
A Review, Block & Mead, Integr.
Cancer Ther. 2003; 2 (3): 247-267.
Chinese Medicinal Herbs Reverse Macrophage Suppression
Induced by Urological Tumors, Rittenhouse, Lui & Lau, J. Urol. 1991; 146 (2): 486-490.
Integrating Chinese & Conventional Medicine in
Colorectal Cancer Treatment, Lahans, Integr. Cancer Ther. 2007; 6 (1): 89-94.
Chinese Herbal Medicine and Chemotherapy in the Treatment of
Hepatocellular Carcinoma: A Meta-analysis of Randomized Controlled Trials, Shu,
McCulloch, Xiao, et al., Integr. Cancer Ther. 2005; 4 (3): 219-229.
Traditional Chinese
Medicine Herbal Treatment May Have a Relevant Impact on the Prognosis of
Patients with Stage IV Adenocarcinoma of the Lung Treated with
Platinum-Based Chemotherapy or Combined
Targeted Therapy and Chemotherapy, Guo, Liu, Xu, et al., Integr. Cancer
Ther. 2011; 10 (2): 127-137.
“And What Other Medications Are You Taking?” , Gordan, Chay,
Kelly, et al., J. Clin. Oncol. 2011: 29 (11): 288-291. {Reishi for primary liver HCC}
Chinese Herbal Medicine for Cancer Pain, Xu, Lao, Ge, et
al., Integr. Cancer Ther. 2007; 6 (3): 208-234.
Cancer Chemo-preventative and Therapeutic Activities of Red
Ginseng, Xiaoguang, Hongyan, Xiaohong, et al., J. Ethnopharmacol. 1998; 60 (1): 71-78.
Current Evaluation of the Millennium Phytomedicine- Ginseng
(II): Collected Chemical Entities, Modern Pharmacology, and Clinical
Applications Emanated from Traditional Chinese Medicine, Jia, Zhao & Liang,
Curr. Med. Chem. 2009; 16 (22): 2924-2942.
Sensitization of a Tumor, But Not Normal Tissue, to the
Cytotoxic Effect of Ionizing Radiation Using Panax Notoginseng Extract, Chen ,Wu, Wang , et al., Am. J. Chin. Med. 2001; 29
(3-4): 517-524.
Honokiol, a Multifunctional Antiangiogenic and Antitumor
Agent, Fried & Arbiser, Antioxid. Redox Signal. 2009; 11 (5): 1139–1148.
The Effects of P6 Acupressure in the Prophylaxis of
Chemotherapy-Related Nausea and Vomiting in Breast Cancer Patients,
Molassiotis, Helin, Dabbour, et al., Complement. Ther. Med. 2007; 15 (1): 3-12.
Acupuncture: Role in Comprehensive Cancer Care – A Primer
for the Oncologist and Review of the Literature, Cohen, Menter & Hale,
Integr. Cancer Ther. 2005; 4 (2): 131-143.
Acupuncture as Palliative Therapy for Physical Symptoms and
Quality of Life for Advanced Cancer Patients, Dean-Clower, Doherty-Gilman,
Keshaviah, et al., Integr. Cancer Ther. 2010; 9 (2): 158-167.
The Management of Cancer Related Fatigue After Chemotherapy
with Acupuncture and Acupressure: A Randomized Controlled Trial, Molassiotis,
Sylt & Diggins, Complement. Ther.
Med. 2007; 154: 228-237.
Acupuncture to Alleviate Chemotherapy-induced Nausea and
Vomiting in Paediatric Oncology – A Randomized Multicenter Cossover Pilot
Trial, Gottschling, Reindl, Meyer, et al., Klin. Paediatr. 2008; 220 (6):
365-370.
Acupuncture for the Treatment of Vasomotor Symptoms in
Breast Cancer Patients Receiving Hormone Suppression Treatment, Walker, et al.,
Int. J. Rad. Oncol. – Biol. – Phys.
2008; Abstract No. 228. Volume 72, Number 1.
Acupuncture-Point Stimulation for Chemotherapy-Induced
Nausea or Vomiting, Ezzo, Richardson,Vickers, et al., Cochrane Database Syst. Rev.
2006; 2: CD002285. DOI:10.1002/14651858.
CD002285.pub2.
Cochrane Review Summary for Cancer Nursing:
Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea or Vomiting,
Konno, Cancer Nurs. 2010; 33 (6): 479-480.
Acupuncture Versus Venlafaxine for the Management of
Vasomotor Symptoms in Patients with Hormone Receptor-Positive Breast Cancer: A
Randomized Controlled Trial, Walker, Rodrigues, Kohn, et al., J. Clin. Oncol.
2009; Epub ahead of print PMID: 20038728.
Acupuncture in the Rehabilitation of Women After Breast
Cancer Surgery- A Case Series, Alem & Gurgel, Acup. Med. 2008; 262: 86-93.
Monitoring of Neuromuscular Blockade at the P6 Acupuncture
Point Reduces the Incidence of
Post-operative Nausea and Vomiting, Arnberger, Stadelmann, Alischer, et
al., Anesthesiology 2007; 107 (6): 903-908.
Clinical Observations on Post-operative Vomiting Treated by
Auricular Acupuncture, Kim, Kim &
Kim, Am. J. Chin. Med. 2003; 31 (3): 475-480.
Clinical Uses of P6 Acupuncture Anti-emesis, Dundee &
McMillan, Acup. Electrother. Res. 1990;
15 (3-4): 211-215.
Acupuncture for Nausea and Vomiting: An Update of Clinical
and Experimental Studies, Streitberger,
Ezzo & Schneider, Auton. Neurosci. 2006; 129( 1-2): 107-117.
Effect of Acupressure on Nausea and Vomiting Induced by
Chemotherapy in Cancer Patients, Gardani, Cerrone, Biella, et al., Minerva Med. 2006; 97 (5): 391-394.
Electroacupuncture for Refractory Acute Emesis Caused by
Chemotherapy, Choo, Kong, Lim, et al.,
J. Altern. Complement. Med. 2006; 12 (10): 963-969.
Acupuncture-point Stimulation for Chemotherapy-Induced
Nausea or Vomiting, Ezzo, Richardson, Vickers, et al., Cochrane Database Syst.
Rev. 2006; (2): CD002285.
Effects of Electro-acupuncture on T-cell Subpopulations, NK
Activity, Humoral Immunity and Leukocyte Count in Patients Undergoing
Chemotherapy, Ye, Liu, Wang & Xu, J.
Trad. Chin. Med. 2007; 271: 19-21.
Acupuncture for the Treatment of Hot Flashes in Breast
Cancer Patients, a Randomized, Controlled Trial, Hervik & Mjaland, Breast Cancer Res. Treat.
2009; 1162: 311-316.
Acupuncture-Point Stimulation for Chemotherapy-Induced
Nausea or Vomiting, Ezzo, Richardson,
Vickers, et al., Cochrane Database of Systematic Reviews 2006; 2: CD002285.
Acupuncture for Dysphagia After Chemo-radiation Therapy in
Head and Neck Cancer: A Case Series Report, Lu, Posner, Wayne, et al., Integr.
Cancer Ther. 2010; 9 (3): 284-290.
Acupuncture versus Metoclopramide in the Treatment of
Postoperative Gastroparesis Syndrome in Abdominal Surgical Patients: A
Randomized Controlled Trial, Sun, Luo, Wu, et al., J. Chin. Integr. Med. 2010;
8 (7): 641.
CO-ENZYME Q10
Coenzyme Q10 Plasma Levels Predict Melanoma Metastasis,
Rusciani, et al, J. Am. Acad.
Dermatology, 2006; 54: 234-241.
Coenzyme Q Differentially Modulates Phospholipid
Hydroperoxide Glutathione Peroxidase Gene Expression and Free Radicals
Production in Malignant and Non-malignant Prostate Cells, Quiles, Farquharson,
Ramirez-Tortosa, et al., Biofactors 2003; 18 (1-4): 265-270.
Clinical Response of Myelodysplastic Syndromes Patients to
Treatment with Coenzyme Q10, Galili, Sechman, Cerny, et al., Leuk Res. 2007 J;
31 (1): 19-26.
Coenzyme q10 for Prevention of Anthracycline-induced
Cardiotoxicity, Conklin, Integr Cancer Ther. 2005; 4 (2): 110-130.
CoQ10: Could It Have
a Role in Cancer Management?, Hodges, Hertz, Lockwood & Lister, BioFactors 1999; 9: 365-370.
An Analysis of the Role of Coenzyme Q in Free Radical
Generation and As an Antioxidant, Beyer, Biochem. & Cell Biol.1992; 70 (6):
390-403.
The Mode of Action of Lipid-soluble Antioxidants in
Biological Membranes. Relationship Between the Effects of Ubiquinol and Vitamin
E as Inhibitors of Lipid Peroxidation in Submitochondrial Particles, Ernster,
Forsmark & Nordenbrand, J. Nutr. Sci. & Vitamin. 1992; Spec No:
548-551.
Improved Survival in Patients with End-Stage Cancer Treated
with Coenzyme Q10 and Other Antioxidants, Hertx & Lister, J. Int. Med. Res.
2009; 37: 1961-1971.
CURCUMIN & INFLAMMATION
Curcumin and Green Tea Polyphenols: Synergistic Anticancer
Compounds, Yarnell, Quart. Rev. Nat. Med. 1998; Fall: 218-220.
Antioxidant and Anti-inflammatory Properties of Curcumin,
Menon & Sudheer, Adv. Exp. Med. Biol. 2007; 595: 105-125.
Curcumin and Resveratrol Inhibit Nuclear
Factor-kappaB-mediated Cytokine Expression in Adipocytes, Gonzales &
Orlando, Nutr. Metab. (Lond). 2008; 5 (1): 17.
Regulation of COX and LOX by Curcumin, Rao, Adv. Exp. Med.
Biol. 2007; 595: 213-226.
Induction of Apoptosis by Curcumin and its Implications for
Cancer Therapy, Karunagaran, Rashmi
& Kumar, Curr. Cancer Drug Targets 2005; 5 (2): 117-129.
Biological Effects of Curcumin and its Role in Cancer
Chemoprevention and Therapy, Singh & Khar, Anticancer Agents Med.Chem.
2006; 6 (3): 259-270.
Chemotherapeutic Potential of Curcumin for Colorectal
Cancer, Chauhan, Curr. Pharm. Des. 2002; 8 (19): 1695-1706.
Curcumin Dually Inhibits Both mTOR and NF-{kappa}B Pathways
Through a Crossed PI3K/Akt/IKK Signaling Axis in Adenoid Cystic Carcinoma, Sun,
Chen, Zhang, et al., Mol. Pharmacol. 2010; [Epub ahead of print] PMID:
20959361.
Synergistic Inhibitory Effects of Curcumin and
5-FluoroUracil on the Growth of the Human Colon Cancer Cell Line HT-29, Du, Jiang, Xia & Zhong, Chemotherapy
2006;52 (1): 23-28.
Curcumin Inhibits Human Colon Cancer cell Growth by
Suppressing Gene Expression of Epidermal Growth Factor Receptor Through
Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu &
Johnson, Oncogene 2005; Sept. 19, Epub.
Molecular Targets of Curcumin, Lin, Adv. Exp. Med. Biol.
2007; 595: 227-243.
Curcumin, an Anti-oxidant and Anti-tumor Promoter, Induces
Apoptosis in Human Leukemia Cells, Kuo, Huang & Lin, Biochem Biophys Acta 1996; 131 (7): 95-100.
The Chemopreventive Agent Curcumin is a Potent
Radiosensitizer of Human Cervical Tumor Cells via Increased Reactive Oxygen
Species Production and Overactivation of the Mitogen-activated Protein Kinase
Pathway, Javvadi, Segan, Tuttle & Koumenis,
Mol Pharmacol. 2008 May; 73 (5): 1491-501.
Curcumin, a Dietary Component, has Anti-cancer,
Chemo-sensitization, and Radio-sensitization Effects by Down-regulating the
MDM2 Oncogene Through the P13K/mTOR/ETS2 Pathway, Zhang, Hill, Wang &
Zhang, Cancer Res. 2007; 67 (5): 1988-1996.
Cellular Foundation of Curcumin-induced Apoptosis in
Follicular Lymphoma Cell Lines, Skommer, Wlodkowic & Pelkonen, Exp.
Hematol. 2006; 34 (4): 463-474.
Curcumin Inhibits Human Colon Cancer Cell Growth by
Suppressing Gene Expression of Epidermal Growth Factor Receptor Through
Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu & Johnson, Oncogene 2006; 25: 278-287.
Therapeutic Potential of Curcumin in Human Prostate
Cancer-1. Curcumin Induces Apoptosis in
Both Androgen-dependent and Androgen-independent Prostate Cancer Cells, Dorai, Gehani & Katz, Prost. Cancer Prost. Dis. 2000; 3: 84-93.
Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in
Models of Human Breast Cancer, Somasundaram, Edmund, Moore, et al., Cancer
Res. 2002; 62 (13): 3868-3875.
Can a Common Spice be Used to Treat Cancer?, Witter,
Oncolog. 2007; 52 (9): 4-5.
Curcumin and Colorectal Cancer: Add Spice to Your Life,
Kunnumakarra, Guha &Aggarwal, Curr. Colorect. Cancer Rep. 2009; 5: 5-14.
Curcumin as Chemosensitizer, Limtrakul, Adv. Exp. Med. Biol.
2007; 595: 269-300.
Chemopreventive and Therapeutic Effects of Curcumin
[Mini-Review],Duvoix, Blasius, Delhalle, et al., Cancer Letters 2005; 223:
181–190.
Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in
Models of Human Breast Cancer, Somasundaram, Edmund, Moore, et al., Cancer Res.
2002; 62 (13): 3868-3875.
Modulation of Function of Three Drug Transporters,
P-Glycoprotein (ABCB1), Mitoxantrone Resistance Protein (ABCG2) and Multi-drug
Resistance Protein 1 (ABCC1) by Tetrahydrocurcumin, a Major Metabolite of Curcumin,
Limtrakul, Chearwae, Shukia, et al., Mol. Cell
Biochem. 2007; 296 (1-2): 85-95.
Aspirin, COX-2 Inhibitors Effective as Adjuvant Therapy in
Stage III Colon Cancer, Fuchs, Amer. Soc. Clin. Onc., AGM May 16, 2005; Abstract 3530, as reported by
Schuster, Medscape Medical News, May 2005; article 504976.
Helicobacter Infection, Chronic Inflammation and the
Development of Malignancy, Crowe, Curr. Opin. Gastroenterol. 2005; 21 (1):
32-38.
Nutritional and Botanical Modulation of the Inflammatory
Cascade – Eicosanoids, Cyclooxygenases and Lipoxygenases – As an Adjunct in
Cancer Therapy, Wallace, Integr. Cancer
Ther. 2002; 1 (1): 7-37.
Inflammation, COX-2 Inhibitors, & Cancer, Block, Integr.
Cancer Ther. 2005; 4 (1): 3-4.
Inflammation and Cancer: An Ancient Link with Novel
Potentials, Perwez Hussain & Harris,
Int. J. Cancer 2007; 121 (11):
2373-2380.
NF-kappaB: A Stress-regulated Switch for Cell Survival,
Piva, Belardo & Santoro, Antioxid.
Redox Signal. 2006; 8 (3-4): 478-486.
Cancer Cachexia and Targeting Chronic Inflammation: A
Unified Approach to Cancer Treatment and Palliative/Supportive Care,
MacDonald, J. Support. Oncol. 2007; 5
(4): 157-162.
Inflammation and Cancer, Coussens & Werb, Nature 2002;
420 (6917): 860-867.
Significance and Relationship Between Infiltrating
Inflammatory Cell and Tumor Angiogenesis in Hepatocellular Carcinoma Tissues,
Peng, Deng, Yang, et al., World J
Gastroenterol. 2005; 11 (41): 6521-6524.
Inflammatory Cell Infiltration of Tumors: Jekyll or Hyde,
Talmadge, Donkor, & Scholar, Cancer
Metastasis Rev. 2007; 26 (3-4): 373- 400.
Bioavailability of Curcumin: Problems and Promises, Anaand,
Kunnumakkara, Newman, et al., Molec. Pharm. 2007; 4 (6): 807-818.
Phase II Trial of Curcumin in Patients with Advanced
Pancreatic Cancer, Dhillon, Aggarwal, Newman, et al., Clin. Cancer Res. 2008;
14 (14): 4491-4499.
Inflammation and
Prostate Cancer, Vasto, Carruba, Candore, et al., Future Oncol. 2008; 4 (5):
637-645.
Prevention and Treatment of Pancreatic Cancer by Curcumin in
Combination with Omega-3 Fatty Acids, Swamy, Citineni, et al, Nutr. Cancer 2008; 60 Suppl. 1: 81-89.
Curcumin Inhibits Human Colon Cancer Cell Growth by
Suppressing Gene Expression of Epidermal Growth Factor Receptor Through
Reducing the Activity of the Transcription Factor Egr-1, Chen, Xu &
Johnson, Oncogene 2006; 25 (2): 278-287.
Phase II Trial of Curcumin in Patients with Advanced
Pancreatic Cancer, Dhillon, Aggarwal, Newman, et al., Clin. Cancer Res. 2008;
14 (14): 4491-4499.
Inhibitory Effect of Curcumin, a Food Spice from Turmeric,
on Platelet-activating Factor and Arachidonic Acid-mediated Platelet
Aggregation Through Inhibition of Thromboxane Formation and Ca2+ Signalling,
Shah, Nawaz, Pertani, et al., Biochem. Pharmacol. 1999; 58 (7): 1167-1172.
Combination Treatment with Curcumin and Quercetin of
Adenomas in Familial Adenomatous Polyposis, Cruz-Correa, Shoskes, Sanchez, et
al., Clin. Gastroenterol. Hepatol. 2006; 4 (8): 1035-1038.
Curcumin Inhibits Proliferation, Invasion, Angiogenesis and
Metastasis of Different Cancers Through Interaction with Multiple Cell
Signaling Proteins, Kunnumakkara, Anand &Aggarwal, Cancer Lett. 2008;[Epub
ahead of print].
Curcumin (Diferuloylmethane) Down-regulates Expression of
Cell Proliferation and Anti-apoptotic and Metastatic Gene Products Through
Suppression of I-kappaB-alpha Kinase and Akt Activation, Aggarwal, Ichikawa,
Takada, et al., Mol. Pharmacol. 2006; 69 (1): 195-206.
Curcumin Down-Regulates the Multidrug-resistance Mdr1b Gene
by Inhibiting the PI3K/Akt/NF kappa B Pathway, Choi, Kim, Lim, et al., Cancer
Lett. 2008; 259 (1): 111-118.
Amelioration of Immune Cell number Depletion and
Potentiation of Depressed Detoxification System of Tumor-bearing Mice by
Curcumin, Pal, Bhattacharyya, Choudhuri, et al., Cancer Detect. Prev. 2005; 29
(5): 470-478
Vitamin Antioxidants, Lipid Peroxidation, Tumour Stage, the
Systemic Inflammatory Response and Survival in Patients with Colorectal Cancer,
Leung, Crozier, Talwar, et al., Int. J. Cancer
2008; 12310: 2460-2464.
Evaluation of Anti-inflammatory Property of Curcumin
(diferuloyl methane) in Patients with Postoperative Inflammation, Satoskar,
Shah & Shenoy, Int. J. Clin.
Pharmacol. Ther. Toxicol. 1986; 24: 651-654.
Biological Effects of Curcumin and its Role in Cancer
Chemoprevention and Therapy, Singh & Khar,
Anticancer Agents Med. Chem. 2006; 6 (3): 259-270.
Chemotherapeutic Potential of Curcumin for Colorectal
Cancer, Chauhan, Curr. Pharm. Des. 2002; 8 (19): 1695-1706
Suppression of the Nuclear Factor-kappaB Activation Pathway
by Spice-derived Phytochemicals: Reasoning for Seasoning, Aggarwal &
Shishodia, Ann. N. Y. Acad. Sci. 2004; 1030: 434-441.
Phase I Dose Escalation Trial of Docetaxol Plus Curcumin in
Patients with Advanced and Metastatic Breast Cancer, Bayet-Robert, Kwiatkowski,
Leheurteur, et al., Cancer Biol. Ther. 2010, 9 (1): [Epub ahead of print}. PMID
19901561.
Curcumin in Combination with Bortezomib Synergistically
Induced Apoptosis in Human Multiple Myeloma U266 Cells, Park, Ayyappan, Bae, et
al., Molecular Oncology 2009 2 (4): 317-326.
Curcumin Circumvents Chemoresistance in vitro and
Potentiates the Effect of Thalidomide and Bortezomib Against Human Multiple
Myeloma in Nude Mice Model, Sung, Kunnumakkara, Sethi, et al., Mol. Cancer
Ther. 2009; 8 (4): 959-970.
Curcumin as an Anti-cancer Agent: Review of the Gap Between
Basic and Clinical Applications, Bar-Sela, Epelbaum & Schaffer, Curr. Med.
Chem. 2010; 17 (3): 190-197(8).
Aromatase Inhibitor Letrozole in Synergy with Curcumin in
the Inhibition of Xenografted Endometrial Carcinoma Growth, Liang, Hao, Wu, et
al., Int. J. Gynecol. Cancer 2009; 19 (7): 1248-1252.
Curcumin Inhibits Prosurvival Pathways in Chronic
Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in
Combination with EGCG, Ghosh, Kay, Secreto & Shanafelt, Clin. Cancer Res.
2009; 15 (4): 1250-1258.
Elimination of Colon Cancer Stem-like Cells by the Combination
of Curcumin and FOLFOX, Yu, Kanwar, Patel, et al., Transl. Oncol. 2009; 2 (4):
321-328.
Curcuma wenyujin Extract Induces Apoptosis and Inhibits
Proliferation of Human Cervical Cancer Cells in Vitro and in Vivo, Lim, Ky, Ng,
et al., Integr. Cancer Ther. 2010; 9 (1): 36-49.
Phase I/II Study of Gemcitabine-based Chemotherapy Plus
Curcumin for Patients with Gemcitabine-resistant
Pancreatic Cancer, Kanai, Yoshimura, Asada, et al., Cancer
Chemother. Pharmacol. 2010; published online Sept. 22, 2010: DOI 10.1007/s00280-010-1470-2A.
Comparison of Systemic Availability of Curcumin with that of
Curcumin Formulated with Phosphatidylcholine, Marczylo, Verschoyle, Cooke, et
al., Cancer Chemother. Pharmacol. 2007;
60 (2):171-177.
Curcumin Inhibits GPVI-Mediated Platelet Activation by
Interfering with the Kinase activity of Syk and the Subsequent Activation of
PLCgamma2, Mayanglambam, Dangelmaier, Thomas, et al., Platelets 2010; 21 (3):
211-220.
Curcumin Dually Inhibits Both mTOR and NF-{kappa}B Pathways
Through a Crossed PI3K/Akt/IKK Signaling Axis in Adenoid Cystic Carcinoma, Sun,
Chen, Zhang, et al., Mol. Pharmacol. 2010; [Epub ahead of print] PMID:
20959361.
Curcumin: A Novel Nutritionally Derived Ligand of the
Vitamin D Receptor with Implications for Colon Cancer Chemoprevention, Bartika,
Whitfielda, Kaczmarskaa, et al., J. Nutr. Biochem. 2010; 21: 1153–1161.
Novel STAT3 Phosphorylation Inhibitors [from Curcumin
]Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer
Cells, Lin, Hutzen, Zuo, et al., Cancer Res. 2010; 70 (6): 2445-2454.
Protective Effect of Curcumin in Cisplatin-Induced Oxidative
Injury in Rat Testis: Mitogen-Activated Protein Kinase and Nuclear Factor-kappa
B Signaling Pathways, Ilbey, Ozbek,
Cekmen, et al., Human Reproduction 2009; 24 (7): 1717–1725.
Curcumin Inhibits Pro-survival Pathways in Chronic
Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in
Combination with EGCG, Ghosh, Kay, Secreto & Shanafelt, Clin. Cancer Res.
2009; 15 (4): 1250-1258.
Curcumin Induces Downregulation of E2F4 Expression and
Apoptotic Cell Death in HCT1116 Human Colon Cancr Cells: Involvement of
Reactive Oxygen Species, Kim & Lee, Korean J. Physiol. Pharmacol. 2010; 14
(6): 391-397.
Curcumin in Cancer Chemoprevention: Molecular Targets,
Pharmacokinetics,Bioavailability, and Clinical Trials, Shehzad, Wahid &
Lee, Arch. Pharm. (Weinheim). 2010; 343 (9): 489-499.
Pharmacokinetics and Pharmacodynamics of Curcumin. Sharma, Steward & Gescher, Adv.
Exp. Med. Biol. 2007; 595: 453-470.
Curcumin Suppresses Human Papillomavirus Oncoproteins,
Restores p53, Rb, and PTPN13 Proteins and Inhibits Benzo[a]pyrene-induced
Upregulation of HPV E7, Maher, Bell, O'Donnell, et al., Mol. Carcinog. 2011; 50
(1): 47-57.
Curcumin Counteracts the Proliferative Effect of Estradiol
and Induces Apoptosis in Cervical Cancer Cells, Singh & Singh, Mol. Cell
Biochem. 2011; 347 (1-2):1-11.
Molecular Mechanism of Curcumin Induced Cytotoxicity in
Human Cervical Carcinoma Cells, Singh & Singh, Mol. Cell Biochem. 2009; 325
(1-2):107-119.
Upregulation of p53 Expression in Patients with Colorectal
Cancer by Administration of Curcumin, He, Shi, Wen, et al., Cancer Inv. 2011;
29: 208–213.
Regression of Follicular Lymphoma with Devil’s Claw:
Coincidence or Causation?, Wilson, Curr. Oncol. 2009; 16 (4): 67-70.
DIET & GENERAL INTEGRATIVE ONCOLOGY
Natural Health Products and Cancer Treatment, Hal Gunn,
Complementary Corner, Summer 2003 Vol. 4 No. 3 www.abreastinthewest.ca (BCCA policy re: natural agents)
Multivitamin Use and Breast Cancer Incidence in a
Prospective Cohort of Swedish Women, Laarson, Akesson, Bergkvist &
Wolk, Am. J. Clin. Nutr. 2010; 91 (5):
1268-1272.
Use of Complementary / Integrative Nutritional Therapies
During Cancer Treatment: Implications in Clinical Practice, Kumar et al.,
Canc. Control 2002; 9 (3):
236-243.
Complementary Therapies for Cancer-related Symptoms, Deng,
Cassileth & Yeung, J. Support Oncol. 2004; 2: 419-429.
Complementary and Alternative Therapies for Cancer,
Cassileth & Deng, Oncologist 2004; 9: 80-89.
Integrative Oncology: Complementary Therapies in Cancer
Care, Cassileth, Heitzer & Gubili, Cancer Chemother. Rev. 2008; 3 (4):
204-211.
Lifestyle changes and the ‘spontaneous’ regression of
cancer: An initial computer analysis
Foster, Int. J. Biosoc. Res., 1988; 10 (1): 17-33.
Exercise in Prevention and Management of Cancer, Newton
& Galvao, Curr. Treat. Opt. Oncol. 2008; 92 (3): 135-146.
Forgiveness Can Improve Immune Function, Owen, Soc. Behav.
Med. 32nd Annual Meeting and Scientific Sessions: Abstract 4010. Presented
April 30, 2011.
Molecular Targets of Dietary Agents for Prevention and
Therapy of Cancer, Aggarwal & Shishodia, Biochem. Pharmacol. 2006; 71:
(10): 1397-1421.
Analysis of Botanicals and Dietary Supplements for
Antioxidant Capacity: a Review, Prior
& Cao, J. AOAC Int. 2000; 83 (4):
950-956.
(Gamma)É£-Tocopherol Traps Mutagenic Electrophiles Such As
NOx and Complements (Alpha)Ī±-Tocopherol: Physiological Implications, Christen,
Woodall, Shigenaga, et al., Proc. Natl. Acad. Sci. 1997; 94: 3217-3222.
Dietary Fat, Fiber, Vegetable, and Micronutrients are
Associated with Overall Survival in Postmenopausal Women Diagnosed with Breast
Cancer, McEligot, Largent, Ziogas, Peel & Anton-Culver, Nutr. Cancer. 2006; 55 (2): 132-140.
Dietary Influences on Survival After Ovarian Cancer, Nagle,
Purdie, Webb, et al., Int. J. Cancer 2003; 106 (2): 264-269.
Association of Dietary Patterns with Cancer Recurrence and
Survival in Patients with Stage III Colon Cancer, Meyerhardt , Niedzwiecki ,
Hollis, et al., J. Amer. Med. Assoc.
2007; 298 (7):754 -764.
Greater Survival After Breast Cancer in Physically Active
Women with High Vegetable-Fruit Intake Regardless of Obesity, Pierce,
Stefanick, Flatt, et al., J. Clin. Oncol. 2007; 25 (17): 2345-2351.
Influence of a Diet Very High in Vegetables, Fruit and Fiber
and Low in Fat on Prognosis Following Treatment for Breast Cancer, J. Amer.
Med. Assoc. 2007; 298 (3): 289-298.
Baseline Nutritional Status is Predictive of Response to
Treatment and Survival in Patients treated by Definitive Chemo-Radiotherapy for
a Locally Advanced Esophageal Cancer, Di Fiore, Lecleire, Pop, et al., Am. J.
Gastroenterol. 2007; 102 (11): 2557-2563.
Is Voluntary Vitamin and Mineral Supplementation Associated
with Better Outcome in Non-Small Cell Lung Cancer Patients? Results from the
Mayo Clinic Lung Cancer Cohort. Jatoi, Williams, Nichols, et al., Lung Cancer. 2005; 49 (1): 77-84.
Cancer and Natural Medicine – a Textbook of Basic Science
and Clinical Research , John Boik, 1996 Oregon Medical Press.
Naturally There’s Hope – A Handbook for the Naturopathic
Care of Cancer Patients, McKinney, Trafford Press, 2003.
Survival Impact of Integrative Cancer Care in Advanced
Metastatic Breast Cancer, Block,
Gyllenhaal, Tripathy, et al., In press, The Breast Journal 2009; 15 (4).
Survival Impact of Integrative Care in Advanced Prostate
Cancer, Block, Gyllenhaal, Chodak, et al., Proc. Am. Soc. Clin. Oncol. 2003;
22: abstract 1746.
Mind-body Therapies for the Management of Pain, Astin, Clin.
J. Pain 2004; 20 (1): 27-32.
Pilot Crossover Trial of Reiki vs. Rest for Treating
Cancer-related Fatigue, Tsang, Carlson & Olson, Integr. Cancer Ther. 2007;
6 (1): 25-35.
Efficacy of Homeopathic Therapy in Cancer Treatment, Milazzo, Russell & Ernst, Eur. J. Cancer, 2006; 42 : 282-289.
Effect of Homeopathic Medicines on Transplanted Tumors in
Mice, Sunila, Kuttan, Preethi & Kuttan, Asian Pac. J. Cancer Prev. 2007; 8:
390-394.
Series of Case Reports: Clinical Evaluation of a Complex
Homeopathic Injection Therapy in the Management of Pain in Patients After
Breast Cancer Treatment, Orellana, Ruiz de ViƱaspre & Kaszkin-Bettag,
Altern. Ther. Health Med. 2010; 16 (1): 54-59.
Cytotoxic Effects of Ultra-diluted Remedies on Breast Cancer
Cells, Frenkel, Mishra, Sen, et al.,
Int. J. Oncol. 2010; 36 (2): 395-403.
PMID: 20043074
The Effect of Thiamine Supplementation on Tumour
Proliferation: A Metabolic Control Analysis Study,
ComƵĆn-Anduix, Boren, Martinez, et al., Eur. J. Biochem.
2001; 268: 4177- 4182.
The Hoxsey Treatment: Cancer Quackery or Effective
Physiological Adjuvant?, Brinker, J.
Naturopathic Med. 1996; 6(1): 9-23.
Broad in vitro Efficacy of Plant-derived Betulinic Acid
Against Cell Lines Derived from the Most Prevalent Human Cancer Types, Kessler,
Mullauer, dee Roo & Medema, Cancer Lett. 2007; 251 (1): 132-145
Complementary & Alternative Medicine, Larson, Trustee
Mag. 2006, Sept.
Survival Impact of Integrative Care in Advanced Prostate
Cancer, Block, Gyllenhaal, Chodak et al.,
Proc. Am Soc Clin Oncol. 2003; 22: abstract 1746.
Survival Impact of Integrative Cancer Care in Advanced
Metastatic Breast Cancer, Block, Gyllenhaal, Tripathy et al., The Breast
Journal. 2008; in press.
Natural Compounds in Cancer Therapy – Promising Non-toxic
Anti-tumor Agents from Plants and Other Natural Sources, John Boik, Oregon
Medical Press 2001.